Acinic cell carcinoma (lung)
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Synonym Attributes
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was changed:
Acinic cell carcinoma of the lung (also known as a Fechner tumour) is a type of lung carcinoma of the salivary gland type. It is extremely rare especially when it presents in the form of a primary acinic cell carcinoma.
Pathology
Histologically, they comprise of clear cells with abundant granular cytoplasm growing as solid sheets with focal acinar, microcystic, and papillocystic regions. Immunohistochemical stains tend to show strong positivity for
- low-molecular-weight cytokeratins
- epithelial membrane antigen (EMA)
.
Radiographic features
CT chest
Can be variable ranging from 1
- subpleural nodules in proximity to secondary bronchi
- endobronchial tumours leading obstructive symptoms
- well-circumscribed deep parenchymal nodules
.
Treatment and prognosis
They tend to have a more indolent behavior and favorable prognosis than other lung tumours.
See also
-
acinic cell carcinoma
- acinic cell carcinoma of the salivary glands
- acinic cell carcinoma of the lung
-<p><strong>Acinic cell carcinoma of the lung</strong> (also known as a <strong>Fechner tumour</strong>) is a type of <a title="Lung carcinoma of the salivary gland type" href="/articles/lung-carcinomas-of-the-salivary-gland-type">lung carcinoma of the salivary gland type</a>. </p><h4>Pathology</h4><p>Histologically, they comprise of clear cells with abundant granular cytoplasm growing as solid sheets with focal acinar, microcystic, and papillocystic regions. Immunohistochemical stains tend to show strong positivity for</p><ul>- +<p><strong>Acinic cell carcinoma of the lung</strong> (also known as a <strong>Fechner tumour</strong>) is a type of <a href="/articles/lung-carcinomas-of-the-salivary-gland-type">lung carcinoma of the salivary gland type</a>. It is extremely rare especially when it presents in the form of a primary acinic cell carcinoma.</p><h4>Pathology</h4><p>Histologically, they comprise of clear cells with abundant granular cytoplasm growing as solid sheets with focal acinar, microcystic, and papillocystic regions. Immunohistochemical stains tend to show strong positivity for</p><ul>
-<li>epithelial membrane antigen (EMA).</li>- +<li>epithelial membrane antigen (EMA)</li>
-<li>well-circumscribed deep parenchymal nodules. </li>- +<li>well-circumscribed deep parenchymal nodules </li>
-<a title="acinic cell carcinoma" href="/articles/acinic-cell-carcinoma">acinic cell carcinoma</a><ul>-<li><a title="Acinic cell carcinoma of salivary glands" href="/articles/acinic-cell-carcinoma-of-salivary-glands">acinic cell carcinoma of the salivary glands</a></li>- +<a href="/articles/acinic-cell-carcinoma">acinic cell carcinoma</a><ul>
- +<li><a href="/articles/acinic-cell-carcinoma-of-salivary-glands">acinic cell carcinoma of the salivary glands</a></li>
-</li></ul><p> </p>- +</li></ul>
References changed:
- 1. Moran CA, Suster S, Koss MN. Acinic cell carcinoma of the lung ("Fechner tumor"). A clinicopathologic, immunohistochemical, and ultrastructural study of five cases. Am. J. Surg. Pathol. 1993;16 (11): 1039-50. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1471724">Pubmed citation</a><span class="auto"></span>
- 2. Lee HY, Mancer K, Koong HN. Primary acinic cell carcinoma of the lung with lymph node metastasis. Arch. Pathol. Lab. Med. 2003;127 (4): e216-9. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12683906">Pubmed citation</a><span class="auto"></span>
- 3. Ukoha OO, Quartararo P, Carter D et-al. Acinic cell carcinoma of the lung with metastasis to lymph nodes. Chest. 1999;115 (2): 591-5. <a href="http://www.ncbi.nlm.nih.gov/pubmed/10027469">Pubmed citation</a><span class="auto"></span>
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