Acinic cell carcinoma of the lung
Acinic cell carcinoma of the lung (also known as a Fechner tumor) is a type of lung carcinoma of the salivary gland type. It is extremely rare especially when it presents in the form of a primary acinic cell carcinoma.
Histologically, they comprise of clear cells with abundant granular cytoplasm growing as solid sheets with focal acinar, microcystic, and papillocystic regions. Immunohistochemical stains tend to show strong positivity for
- low-molecular-weight cytokeratins
- epithelial membrane antigen (EMA).
Can be variable ranging from 1
- subpleural nodules in proximity to secondary bronchi
- endobronchial tumors leading obstructive symptoms
- well-circumscribed deep parenchymal nodules.
Treatment and prognosis
They tend to have a more indolent behavior and favorable prognosis than other lung tumors.