Adie syndrome

Last revised by Subhan Iqbal on 11 Apr 2022

Adie syndrome, also known as Holmes-Adie syndrome, is a rare neurological disorder.

Adie syndrome is a rare condition that is most commonly seen in young females in their fourth decade of life 2,3.

Patients most commonly present with a classic triad of:

  1. diaphoresis
  2. absent deep tendon reflexes, e.g. ankle jerk
  3. an Adie pupil: tonically dilated and responds poorly or not at all to light

Unilateral pupillary symptoms are more common than bilateral 2,3. A few of the other symptoms are emotional fluctuations, headache and facial pain 4.

It is thought to result from damage to the ciliary ganglion and the dorsal root ganglion by viral or bacterial infections, however, there are idiopathic etiologies 1,3.

It was named after the British-Australian neurologist William John Adie (1886 - 1935) 1

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.