Citation, DOI and article data
Patients may be asymptomatic or present with symptoms similar to mechanical bowel obstruction such as nausea/vomiting, distension, and reduced or absent bowel movements. Bowel sounds may also be absent.
Adynamic ileus can be caused by several conditions:
- drugs, e.g. opioids
- metabolic, e.g. hyponatremia
- sepsis: especially gram-negative bacteria
- abdominal trauma or surgery (see below)
- myocardial infarction / congestive heart failure
- head injury or neurosurgery
- intra-abdominal inflammation and peritonitis
- retroperitoneal hematoma
- acute mesenteric ischemia: ileus limited to a vascular territory 10
The cause of ileus is thought to be complex and multifactorial, involving bowel inflammation 6, inhibitory neural reflexes 7, and neurohormonal peptides 8.
Postoperative ileus vs paralytic ileus
Some degree of ileus is a normal and expected finding after abdominal surgery, including C-section 9. Conventional recovery times have been reported as 4:
- small intestine: 0-24 hours
- stomach: 24-48 hours
- colon: 48-72 hours
These intervals, however, may be overestimations 5.
Prolonged postoperative ileus (>72 hours) has been termed "paralytic" ileus by some and is concerning for small bowel obstruction, bowel perforation, peritonitis, and intra-abdominal abscess.
Improving postoperative ileus is often determined clinically as much as radiographically, with the resumption of oral intake and flatus.
- generalized, uniform, gaseous distension of the large and small bowel
- involvement of large bowel and lack of a transition point help distinguish it from small bowel obstruction
- when localized, there may be a sentinel loop
Treatment and prognosis
Improving gastric motility, boosting the nourishment status of the patient, and strengthening the stability of the interior environment are the main motives of therapy 11.
History and etymology
"Ileus" ultimately derives from είλειν ("to twist"), which also gave rise to the section of the bowel termed the "ileum". At one time what we now call ileus had been called the "iliack passion" because it was believed that the intestines were twisted 3.
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- 10. Laura A. Fitzpatrick, Michael D. Rivers-Bowerman, Seng Thipphavong, Sharon E. Clarke, Judy A. Rowe, Andreu F. Costa. Pearls, Pitfalls, and Conditions that Mimic Mesenteric Ischemia at CT. (2020) RadioGraphics. 40 (2): 545-561. doi:10.1148/rg.2020190122 - Pubmed
- 11. Zhu CZ, Zhao HW, Lin HW, Wang F, Li YX. Latest developments in chronic intestinal pseudo-obstruction. (2020) World journal of clinical cases. 8 (23): 5852-5865. doi:10.12998/wjcc.v8.i23.5852 - Pubmed