Ancient schwannoma
Last revised by Frank Gaillard on 24 Feb 2022
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Gaillard F, Iqbal S, et al. Ancient schwannoma. Reference article, Radiopaedia.org (Accessed on 18 Apr 2024) https://doi.org/10.53347/rID-41897
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rID:
41897
Article created:
25 Dec 2015,
Yuranga Weerakkody ◉
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Revisions:
9 times, by
8 contributors -
see full revision history and disclosures
Systems:
Tags:
Synonyms:
- Ancient schwannomas
- Ancient neurilemmoma
Ancient schwannomas are long-standing, benign (WHO grade 1) slow growing schwannomas with advanced degeneration. The term “ancient” has been traditionally used to describe schwannomas showing degenerative changes and diffuse hypocellular ischemic areas 1-3,9.
Pathology
These tumors demonstrate nuclear pleomorphism microscopically, which should not be misinterpreted as malignant features 4,9.
Radiographic features
Features of calcification, hyalinization, and cystic cavitation can be identified on imaging 1-3.
References
- 1. Lin J, Martel W. Cross-sectional imaging of peripheral nerve sheath tumors: characteristic signs on CT, MR imaging, and sonography. AJR Am J Roentgenol. 2001;176 (1): 75-82. doi:10.2214/ajr.176.1.1760075 - Pubmed citation
- 2. Lee YS, Kim JO, Park SE. Ancient schwannoma of the thigh mimicking a malignant tumour: a report of two cases, with emphasis on MRI findings. Br J Radiol. 2010;83 (991): e154-7. doi:10.1259/bjr/19325350 - Free text at pubmed - Pubmed citation
- 3. Isobe K, Shimizu T, Akahane T et-al. Imaging of ancient schwannoma. AJR Am J Roentgenol. 2004;183 (2): 331-6. doi:10.2214/ajr.183.2.1830331 - Pubmed citation
- 4. Louis DN, Ohgaki H, Wiestler OD et-al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007;114 (2): 97-109. Acta Neuropathol. (full text) - doi:10.1007/s00401-007-0243-4 - Free text at pubmed - Pubmed citation
- 5. Stemmer-Rachamimov AO, Jo VY, Rodriguez FJ, Reuss DE, Schwannoma. In: WHO Classification of Tumours Editorial Board. Central nervous system tumours. Lyon (France): International Agency for Research on Cancer; 2021. (WHO classification of tumours series, 5th ed.; vol. 6). https://publications.iarc.fr/601
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