Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Gaillard F, Iqbal S, et al. Ancient schwannoma. Reference article, Radiopaedia.org (Accessed on 18 Apr 2024) https://doi.org/10.53347/rID-41897
Ancient schwannomas are long-standing, benign (WHO grade 1) slow growing schwannomas with advanced degeneration. The term “ancient” has been traditionally used to describe schwannomas showing degenerative changes and diffuse hypocellular ischemic areas 1-3,9.
Pathology
These tumors demonstrate nuclear pleomorphism microscopically, which should not be misinterpreted as malignant features 4,9.
Radiographic features
Features of calcification, hyalinization, and cystic cavitation can be identified on imaging 1-3.
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2. Lee YS, Kim JO, Park SE. Ancient schwannoma of the thigh mimicking a malignant tumour: a report of two cases, with emphasis on MRI findings. Br J Radiol. 2010;83 (991): e154-7. doi:10.1259/bjr/19325350 - Free text at pubmed - Pubmed citation
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3. Isobe K, Shimizu T, Akahane T et-al. Imaging of ancient schwannoma. AJR Am J Roentgenol. 2004;183 (2): 331-6. doi:10.2214/ajr.183.2.1830331 - Pubmed citation
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4. Louis DN, Ohgaki H, Wiestler OD et-al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007;114 (2): 97-109. Acta Neuropathol. (full text) - doi:10.1007/s00401-007-0243-4 - Free text at pubmed - Pubmed citation
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5. Stemmer-Rachamimov AO, Jo VY, Rodriguez FJ, Reuss DE, Schwannoma. In: WHO Classification of Tumours Editorial Board. Central nervous system tumours. Lyon (France): International Agency for Research on Cancer; 2021. (WHO classification of tumours series, 5th ed.; vol. 6). https://publications.iarc.fr/601
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