Anterior choroidal artery syndrome

Changed by Rohit Sharma, 10 Dec 2023
Disclosures - updated 18 Aug 2023: Nothing to disclose

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Anterior choroidal artery syndrome is a rare entity characterisedcaused by the triad of:

  • hemiplegia

  • hemianaesthesia

  • contralateral hemianopia

This occurs as a result of cerebral infarction in the anterior choroidal artery territory territory.

Clinical presentation

In its complete form, the syndrome is characterised by the triad of 7:

  • contralateral hemiplegia

  • contralateral hemisensory loss

  • contralateral homonymous hemianopia

Incomplete forms of the syndrome are more common than that of complete forms 7. The syndrome may also be associated with neuropsychological disorders, including left neglect syndrome in right-sided lesions and disorders of speechlanguage in left-sided lesions.

Incomplete forms of the syndrome are more common than that of complete forms. The incomplete forms include lacunar syndromes and ataxic hemiparesis 57.

Pathology

Aetiology

The complete Complete anterior choroidal artery ichaemic strokes are usually associated with cardioembolic sources anddue to cardioembolism or internal carotid artery stenosis. Smaller strokes (i.e. lacunar strokes) that involve only parts of the territory are typically due to T2traditional cerebrovascular risk factors, such as type 2 diabetes mellitus, hypertension and hyperlipidaemia 5. The classic triad of symptoms isof a complete syndrome are rare to see because of the anastomosis with perforators from the middle cerebral, posterior cerebral and posterior communicating arteries.

DiagnosisDifferential diagnosis

The anterior choroidal artery has an extensive area of supply and large variations in its distributed territory 6. As a result of its extensive and strategic supply, anterior choroidal artery infarcts can often be confused with posterior cerebral artery or middle cerebral artery infarcts 6.

  • -<p><strong>Anterior choroidal artery syndrome</strong> is a rare entity characterised by the triad of:</p><ul>
  • -<li><p>hemiplegia</p></li>
  • -<li><p>hemianaesthesia</p></li>
  • -<li><p>contralateral hemianopia</p></li>
  • -</ul><p>This occurs as a result of <a href="/articles/ischaemic-stroke">cerebral infarction</a> in the <a href="/articles/anterior-choroidal-artery">anterior choroidal artery</a> territory.</p><p>The syndrome may also be associated with neuropsychological disorders, including left neglect syndrome in right-sided lesions and disorders of speech in left-sided lesions.</p><p>Incomplete forms of the syndrome are more common than that of complete forms. The incomplete forms include lacunar syndromes and ataxic hemiparesis <sup>5</sup>.</p><h4>Aetiology</h4><p>The complete anterior choroidal artery strokes are usually associated with cardioembolic sources and carotid stenosis. Smaller strokes that involve only parts of the territory are typically due to T2 diabetes mellitus, hypertension and hyperlipidaemia <sup>5</sup>. The triad of symptoms is rare to see because of the anastomosis with perforators from the middle cerebral, posterior cerebral and posterior communicating arteries.</p><h4>Diagnosis</h4><p>The anterior choroidal artery has an extensive area of supply and large variations in its distributed territory <sup>6</sup>. As a result of its extensive and strategic supply, anterior choroidal artery infarcts can often be confused with posterior cerebral artery or middle cerebral infarcts <sup>6</sup>.</p>
  • +<p><strong>Anterior choroidal artery syndrome</strong> is a rare entity caused by <a href="/articles/ischaemic-stroke">cerebral infarction</a> in the <a href="/articles/anterior-choroidal-artery">anterior choroidal artery</a>&nbsp;territory.</p><h4>Clinical presentation</h4><p>In its complete form, the syndrome is characterised by the triad of <sup>7</sup>:</p><ul>
  • +<li><p>contralateral hemiplegia</p></li>
  • +<li><p>contralateral hemisensory loss</p></li>
  • +<li>
  • +<p>contralateral homonymous hemianopia</p>
  • +<ul>
  • +<li><p>e.g. homonymous quadruple sectoranopia if the <a href="/articles/lateral-geniculate-nucleus-1" title="Lateral geniculate body">lateral geniculate body</a> is involved</p></li>
  • +<li><p>e.g. incongruent homonymous hemianopia if the <a href="/articles/optic-tract" title="Optic tract">optic tract</a> is involved</p></li>
  • +</ul>
  • +</li>
  • +</ul><p>Incomplete forms of the syndrome are more common than that of complete forms <sup>7</sup>. The syndrome may also be associated with neuropsychological disorders, including left neglect syndrome in right-sided lesions and disorders of language in left-sided lesions <sup>7</sup>.</p><h4>Pathology</h4><h5>Aetiology</h5><p>Complete <a href="/articles/anterior-choroidal-artery" title="Anterior choroidal artery">anterior choroidal artery</a> ichaemic strokes are usually due to cardioembolism or <a href="/articles/carotid-artery-stenosis" title="Carotid artery stenosis">internal carotid artery stenosis</a>. Smaller strokes (i.e. lacunar strokes) that involve only parts of the territory are typically due to traditional cerebrovascular risk factors, such as <a href="/articles/diabetes-mellitus" title="Type 2 diabetes mellitus">type 2 diabetes mellitus</a>, <a href="/articles/hypertension" title="Hypertension">hypertension</a> and <a href="/articles/hyperlipidaemia" title="Hyperlipidaemia">hyperlipidaemia</a> <sup>5</sup>. The classic triad of symptoms of a complete syndrome are rare because of the anastomosis with perforators from the <a href="/articles/middle-cerebral-artery" title="Middle cerebral artery">middle cerebral</a>, <a href="/articles/posterior-cerebral-artery" title="Posterior cerebral artery">posterior cerebral</a> and <a href="/articles/posterior-communicating-artery" title="Posterior communicating arteries">posterior communicating arteries</a>.</p><h4>Differential diagnosis</h4><p>The anterior choroidal artery has an extensive area of supply and large variations in its distributed territory <sup>6</sup>. As a result of its extensive and strategic supply, anterior choroidal artery infarcts can often be confused with <a href="/articles/posterior-cerebral-artery" title="Posterior cerebral artery">posterior cerebral artery</a> or <a href="/articles/middle-cerebral-artery" title="Middle cerebral artery">middle cerebral artery</a> infarcts <sup>6</sup>.</p>

References changed:

  • 4. Morris P. Practical Neuroangiography. (2013) ISBN: 9781451144154 - <a href="http://books.google.com/books?vid=ISBN9781451144154">Google Books</a>
  • 7. Palomeras E, Fossas P, Cano A, Sanz P, Floriach M. Anterior Choroidal Artery Infarction: A Clinical, Etiologic and Prognostic Study. Acta Neurol Scand. 2008;118(1):42-7. <a href="https://doi.org/10.1111/j.1600-0404.2007.00980.x">doi:10.1111/j.1600-0404.2007.00980.x</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/18205882">Pubmed</a>
  • 4. Pearse Morris. Practical Neuroangiography. (2007) ISBN: 0781765153

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