Anti-GQ1b IgG antibody syndrome

Last revised by Daniel J Bell on 25 Sep 2018

Anti-GQ1b IgG antibody syndrome refers to a number of conditions which share autoantibodies to the ganglioside complex GQ1b, and have overlapping clinical spectrums. 

The conditions believed to represent various clinical manifestations of a common immunological disorder include 1

The exact relationship between these entities, and what determines the clinical phenotype remains unclear, possibly relating to the exact specificity of the anti-GQ1b antibodies and how these are expressed throughout the nervous system 2

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