Breast lymphoma

Changed by Ayush Goel, 3 Jul 2014

Updates to Article Attributes

Body was changed:

Breast lymphoma refers to involvement of the breast with lymphoma.

Pathology

Breast lymphomas can be either primary or secondary. Both are rare accounting for 0.3 - 1.1 % of all breast malignancies.

Primary lymphoma of the breast is less common than secondary lymphoma, and is typically a B cell type non-Hodgkin's lymphoma (NHL). Primary non-Hodgkin’s lymphoma of the breast representing only 0.12 - 0.53% of all reported malignant breast tumours.

For a tumour to be labeled as a primary breast lymphoma it is required to fulfill the following criteria 5:

  • mammary and lymphatic infiltration should be in close proximity
  • adequate pathological evaluation
  • exclusion of previous extra-mammary or systemic lymphoma

Secondary lymphoma of the breast, is also more frequently NHL than Hodgkin's lymphoma

The axillary nodes are often large. It may present either as a palpable mass or as diffuse thickening of the breast.

Radiographic features

There is no single imaging finding diagnostic of lymphoma, it.

Mammography

It can have variable mammographic appearances but usually it manifests with a diffuse marked increase in parenchymal density (often can be bilateral).

Ultrasound

The sonographic appearance is most often that of a solid hypoechoic mass which is again non specific; both.

Both radiologic and clinical appearance are similar to carcinoma and therefore the differential diagnosis is difficult. Microcalcifications are not a usual feature in lymphoma. 

See also

  • -<p><strong>Breast lymphoma</strong> refers to involvement of the breast with <a title="lymphoma" href="/articles/lymphoma">lymphoma</a>. </p><h4>Pathology</h4><p>Breast lymphomas can be either <strong>primary </strong>or <strong>secondary</strong>. Both are rare accounting for 0.3 - 1.1 % of all breast malignancies.</p><p><a title="Primary lymphoma of the breast " href="/articles/primary-lymphoma-of-the-breast">Primary lymphoma of the breast </a>is less common than secondary lymphoma, and is typically a B cell type <a href="/articles/non-hodgkin-lymphoma">non-Hodgkin's lymphoma</a> (NHL). Primary non-Hodgkin’s lymphoma of the breast representing only 0.12 - 0.53% of all reported malignant breast tumours. </p><p>For a tumour to be labeled as a primary breast lymphoma it is required to fulfill the following criteria <sup>5</sup>:</p><div><ul>
  • +<p><strong>Breast lymphoma</strong> refers to involvement of the breast with <a href="/articles/lymphoma">lymphoma</a>.</p><h4>Pathology</h4><p>Breast lymphomas can be either <strong>primary </strong>or <strong>secondary</strong>. Both are rare accounting for 0.3 - 1.1 % of all breast malignancies.</p><p><a href="/articles/primary-lymphoma-of-the-breast">Primary lymphoma of the breast </a>is less common than secondary lymphoma, and is typically a B cell type <a href="/articles/non-hodgkin-lymphoma">non-Hodgkin's lymphoma</a> (NHL). Primary non-Hodgkin’s lymphoma of the breast representing only 0.12 - 0.53% of all reported malignant breast tumours.</p><p>For a tumour to be labeled as a primary breast lymphoma it is required to fulfill the following criteria <sup>5</sup>:</p><ul>
  • -</ul></div><p><a title="Secondary lymphoma of the breast" href="/articles/secondary-lymphoma-of-the-breast">Secondary lymphoma of the breast</a>, is also more frequently NHL than <a href="/articles/hodgkin-s-lymphoma">Hodgkin's lymphoma</a>. </p><p>The axillary nodes are often large. It may present either as a palpable mass or as diffuse thickening of the breast.</p><h4>Radiographic features</h4><p>There is no single imaging finding diagnostic of lymphoma, it can have variable mammographic appearances but usually it manifests with a diffuse marked increase in parenchymal density (often can be bilateral). The sonographic appearance is most often that of a solid hypoechoic mass which is again non specific; both radiologic and clinical appearance are similar to carcinoma and therefore the differential diagnosis is difficult. Microcalcifications are not a usual feature in lymphoma. </p><h4>See also</h4><ul><li><a title="Breast cancer" href="/articles/breast-neoplasms">breast cancer</a></li></ul>
  • +</ul><p><a href="/articles/secondary-lymphoma-of-the-breast">Secondary lymphoma of the breast</a>, is also more frequently NHL than <a href="/articles/hodgkin-s-lymphoma">Hodgkin's lymphoma</a>. </p><p>The axillary nodes are often large. It may present either as a palpable mass or as diffuse thickening of the breast.</p><h4>Radiographic features</h4><p>There is no single imaging finding diagnostic of lymphoma.</p><h5>Mammography</h5><p>It can have variable mammographic appearances but usually it manifests with a diffuse marked increase in parenchymal density (often can be bilateral).</p><h5>Ultrasound</h5><p>The sonographic appearance is most often that of a solid hypoechoic mass which is again non specific.</p><p>Both radiologic and clinical appearance are similar to carcinoma and therefore the differential diagnosis is difficult. Microcalcifications are not a usual feature in lymphoma. </p><h4>See also</h4><ul><li><a href="/articles/breast-neoplasms">breast cancer</a></li></ul>

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