Callosal angle

Changed by Matthew Lukies, 3 Feb 2018

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The callosal angle has been proposed as a useful marker of patients with idiopathic normal pressure hydrocephalus (iNPH), helpful in distinguishing these patients from those with ex-vacuo ventriculomegaly (see hydrocephalus versus atrophy). 

Method

Ideally the angle should be measured on a coronal image perpendicular to the anterior commissure - posterior commissure (AC-PC) plane at the level of  the posterior commissure 1,2.

Values

In general patients with iNPH have smaller angles than those with ventriculomegaly from atrophy or normal controls. 

A normal value is typically between 100-120°. In patients with iNPH that value is lower, between 50-80° 2.  

In one study, symptomatic iNPH patients who responded to shunting had a significantly smaller mean preoperative callosal angle (59° (95% CI 56°-63°)) compared with those who did not respond (68° (95% CI 61°-75°)) 1

  • -<p>The <strong>callosal angle</strong> has been proposed as a useful marker of patients with <a href="/articles/normal-pressure-hydrocephalus">idiopathic normal pressure hydrocephalus (iNPH)</a>, helpful in distinguishing these patients from those with <a href="/articles/hydrocephalus-ex-vacuo">ex-vacuo ventriculomegaly</a> (see <a href="/articles/hydrocephalus-vs-atrophy-1">hydrocephalus versus atrophy</a>). </p><h4>Method</h4><p>Ideally the angle should be measured on a coronal image perpendicular to the <a href="/articles/ac-pc-line-1">anterior commissure - posterior commissure (AC-PC) plane</a> at the level of  the <a href="/articles/posterior-commissure">posterior commissure</a> <sup>1,2</sup>.</p><h4>Values</h4><p>In general patients with iNPH have smaller angles than those with ventriculomegaly from atrophy or normal controls. </p><p>A normal value is typically between 100-120°. In patients with iNPH that value is lower, between 50-80° <sup>2</sup>.  </p><p>In one study, symptomatic iNPH patients who responded to shunting had a significantly smaller mean preoperative callosal angle (59° (95% CI 56°-63°)) compared with those who did not respond (68° (95% CI 61°-75°)) <sup>1</sup>. </p>
  • +<p>The <strong>callosal angle</strong> has been proposed as a useful marker of patients with <a href="/articles/normal-pressure-hydrocephalus">idiopathic normal pressure hydrocephalus (iNPH)</a>, helpful in distinguishing these patients from those with <a href="/articles/hydrocephalus-ex-vacuo">ex-vacuo ventriculomegaly</a> (see <a href="/articles/hydrocephalus-vs-atrophy-2">hydrocephalus versus atrophy</a>). </p><h4>Method</h4><p>Ideally the angle should be measured on a coronal image perpendicular to the <a href="/articles/ac-pc-line-1">anterior commissure - posterior commissure (AC-PC) plane</a> at the level of  the <a href="/articles/posterior-commissure">posterior commissure</a> <sup>1,2</sup>.</p><h4>Values</h4><p>In general patients with iNPH have smaller angles than those with ventriculomegaly from atrophy or normal controls. </p><p>A normal value is typically between 100-120°. In patients with iNPH that value is lower, between 50-80° <sup>2</sup>.  </p><p>In one study, symptomatic iNPH patients who responded to shunting had a significantly smaller mean preoperative callosal angle (59° (95% CI 56°-63°)) compared with those who did not respond (68° (95% CI 61°-75°)) <sup>1</sup>. </p>
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