Revision 13 for 'Cardiac blood pool scan'

All Revisions - View changeset

Cardiac blood pool scan

A multi-gated (MUGA) cardiac blood scan scan is a common study performed in patients who are receiving potentially cardiotoxic chemotherapy. 


  • acute myocardial infarction (AMI)
  • coronary artery disease (CAD)
  • evaluation after coronary artery bypass graft surgery
  • cardiomyopathy / myocarditis
  • assessment of drug therapy
  • pulmonary disease
    • RV enlargement
    • cor pulmonale
    • normal LV ejection fraction, wall motion and chamber size strongly suggests a pulmonary aeitiology

Tracer dose and route of administration

  • Tc labeled RBC


  • patient in normal sinus rhythm
  • IV administration of Tc Labeled RBC
  • ECG gated – with R wave gating
  • minimum of 16 frames/cardiac cycle
  • at rest and exercise
First pass study

This is obtained by injecting a compact bolus of suitable radiopharmaceutical intravenously.

  • major advantage: data collected rapidly over very few cardiac cycles allows measurement of ventricular function at peak stress during exercise ventriculography
  • major disadvantage: counting statistics are low and only a limited number of views are possible


  • qualitative analysis
  • quantitative analysis
  • functional parameters
    • wall motion assessment (regional and global)
    • ED and ES ventricular volume
    • stroke volume
    • cardiac output
    • ejection fraction ( LV and RV)
    • regurgitant fraction (stroke index ratio)
    • ventricular filling and emptying rates
    • cardiac shunt quantitation
      • left to right shunts – evaluated using the first transit technique (NOT equilibrium)
      • right to left shunts – evaluated using Tc99m labeled macro-aggregated albumin and comparing ratio of tracer in the lung to tracer gaining access to the systemic circulation

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.