Cascade sign (Behçet disease)

Last revised by Rohit Sharma on 12 Feb 2024

Citation, DOI, disclosures and article data

Citation:

Sharma R, Cascade sign (Behçet disease). Reference article, Radiopaedia.org (Accessed on 07 May 2024) https://doi.org/10.53347/rID-183987

DOI:

https://doi.org/10.53347/rID-183987

Permalink:

https://radiopaedia.org/articles/183987

rID:

183987

Article created:

12 Feb 2024, Rohit Sharma ◉

Disclosures:

At the time the article was created Rohit Sharma had no financial relationships to ineligible companies to disclose.

View Rohit Sharma's current disclosures

Last revised:

12 Feb 2024, Rohit Sharma ◉

Disclosures:

At the time the article was last revised Rohit Sharma had no financial relationships to ineligible companies to disclose.

View Rohit Sharma's current disclosures

Revisions:

1 time, by 1 contributor - see full revision history and disclosures

Systems:

Central Nervous System

Sections:

Signs

Tags:

cases

Synonyms:

Cascade sign (neuro-Behçet disease)
Waterfall sign (neuro-Behçet disease)
Waterfall sign (Behçet disease)

The cascade sign, also known as the waterfall sign, is a radiological sign appreciated on MRI brain that is described in patients with neuro-Behçet disease involving the mesodiencephalic junction.

The sign describes the involvement of the mesodiencephalic junction as seen on coronal T2/FLAIR sequences, whereby there is high signal that extends from the thalamus and/or internal capsule caudally to the ipsilateral midbrain ^1-3. This region of high signal often has ill-defined margins and overall, has a shape which resembles a cascade or waterfall ^1-3.