Chronic pulmonary aspergillosis
Last revised by Mohammad Taghi Niknejad on 27 Feb 2024
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Niknejad M, Abdul-Hamid A, et al. Chronic pulmonary aspergillosis. Reference article, Radiopaedia.org (Accessed on 29 Mar 2024) https://doi.org/10.53347/rID-56927
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rID:
56927
Article created:
29 Nov 2017,
Yuranga Weerakkody ◉
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
27 Feb 2024,
Mohammad Taghi Niknejad ◉
Disclosures:
At the time the article was last revised Mohammad Taghi Niknejad had no financial relationships to ineligible companies to disclose.
View Mohammad Taghi Niknejad's current disclosures
Revisions:
6 times, by
4 contributors -
see full revision history and disclosures
Systems:
Synonyms:
- Chronic pulmonary aspergillosis (CPA)
Chronic pulmonary aspergillosis (CPA) is a group of chronic aspergillosis found in non-immunocompromised patients with prior or current lung disease (e.g. chronic obstructive pulmonary disease, mycobacteriosis or conditions such as diabetes).
It can manifest as several forms 1.
- chronic cavitary pulmonary aspergillosis (CCPA): considered the most common form.
- chronic necrotizing pulmonary aspergillosis (CNPA)
- chronic fibrosing pulmonary aspergillosis (CFPA): may progress to this from CCPA in untreated cases
- Aspergillus nodule
- aspergilloma
Clinical presentation
Patients usually present with chronic symptoms such as prolonged and relapsing cough, dyspnea and weight loss. Acute symptoms such as hemoptysis and bronchial or pulmonary hemorrhage may however occasionally occur 3.
Quiz questions
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References
- 1. David W. Denning, Jacques Cadranel, Catherine Beigelman-Aubry, Florence Ader, Arunaloke Chakrabarti, Stijn Blot, Andrew J. Ullmann, George Dimopoulos, Christoph Lange. Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management. European Respiratory Journal. doi:10.1183/13993003.00583-2015 - Pubmed
- 2. Kosmidis C, Denning DW. The clinical spectrum of pulmonary aspergillosis. Thorax. 70 (3): 270-7. doi:10.1136/thoraxjnl-2014-206291 - Pubmed
- 3. Schweer KE, Bangard C, Hekmat K, Cornely OA. Chronic pulmonary aspergillosis. Mycoses. 57 (5): 257-70. doi:10.1111/myc.12152 - Pubmed
- 4. Patterson KC, Strek ME. Diagnosis and treatment of pulmonary aspergillosis syndromes. Chest. 146 (5): 1358-1368. doi:10.1378/chest.14-0917 - Pubmed
- 5. Hedayati MT, Azimi Y, Droudinia A, Mousavi B, Khalilian A, Hedayati N, Denning DW. Prevalence of chronic pulmonary aspergillosis in patients with tuberculosis from Iran. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 34 (9): 1759-65. doi:10.1007/s10096-015-2409-7 - Pubmed
- 6. Desai SR, Hedayati V, Patel K, Hansell DM. Chronic Aspergillosis of the Lungs: Unravelling the Terminology and Radiology. European radiology. 25 (10): 3100-7. doi:10.1007/s00330-015-3690-7 - Pubmed
- 7. Prasad A, Agarwal K, Deepak D, Atwal SS. Pulmonary Aspergillosis: What CT can Offer Before it is too Late!. (2016) Journal of clinical and diagnostic research : JCDR. 10 (4): TE01-5. doi:10.7860/JCDR/2016/17141.7684 - Pubmed
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