Contrast-enhanced ultrasound
Updates to Article Attributes
Contrast enhanced-enhanced ultrasound (CEUS) involves the administration of intravenous contrast agents containing microbubbles of perfluorocarbon or nitrogen gas. The bubbles greatly affect ultrasound backscatter and increase vascular contrast in a similar manner to intravenous contrast agents acting on the propagation of sound waves through tissue.
Most commonly, these agents contain microbubbles of gas, which greatly effects ultrasound backscatter used in CT and MRI 1.
Microbubbles are not filtered in the lungs since they are equivalent in size to red blood cells.
Microbubbles are different than the agitated saline used in echocardiographic "bubble studies".
Non-targeted contrast-enhanced ultrasound
More common method
- dynamic evaluation of the vascularity of a target lesion may be useful in diagnosis
- used to measure organ perfusion, which can be useful in diagnosing diffuse processes (e.g. cirrhosis)
Targeted contrast enhanced-enhanced ultrasound
Contrast agents designed to bind to specific molecules, which are then targeted at tissues expressing that substance.
Non-targeted contrast enhanced ultrasound
Used to measure perfusion and helps in lesion characterization.
-<p><strong>Contrast enhanced ultrasound</strong> (<strong>CEUS</strong>) involves the administration of contrast agents acting on the propagation of sound waves through tissue.</p><p>Most commonly, these agents contain microbubbles of gas, which greatly effects ultrasound backscatter <sup>1</sup>.</p><h5>Targeted contrast enhanced ultrasound</h5><p>Contrast agents designed to bind to specific molecules, which are then targeted at tissues expressing that substance.</p><h5>Non-targeted contrast enhanced ultrasound</h5><p>Used to measure perfusion and helps in lesion characterization.</p>- +<p><strong>Contrast-enhanced ultrasound</strong> (<strong>CEUS</strong>) involves the administration of intravenous contrast agents containing <a href="/articles/microbubbles">microbubbles</a> of perfluorocarbon or nitrogen gas. The bubbles greatly affect ultrasound backscatter and increase vascular contrast in a similar manner to intravenous contrast agents used in CT and MRI <sup>1</sup>.</p><p>Microbubbles are not filtered in the lungs since they are equivalent in size to red blood cells.</p><p>Microbubbles are different than the agitated saline used in echocardiographic "bubble studies".</p><h5>Non-targeted contrast-enhanced ultrasound</h5><p>More common method</p><ul>
- +<li>dynamic evaluation of the vascularity of a target lesion may be useful in diagnosis</li>
- +<li>used to measure organ perfusion, which can be useful in diagnosing diffuse processes (e.g. <a href="/articles/cirrhosis">cirrhosis</a>)</li>
- +</ul><h5>Targeted contrast-enhanced ultrasound</h5><p>Contrast agents designed to bind to specific molecules, which are then targeted at tissues expressing that substance.</p>
References changed:
- 2. Wilson S, Greenbaum L, Goldberg B. Contrast-Enhanced Ultrasound: What Is the Evidence and What Are the Obstacles? AJR Am J Roentgenol. 2009;193(1):55-60. <a href="https://doi.org/10.2214/ajr.09.2553">doi:10.2214/ajr.09.2553</a>
Unable to process the form. Check for errors and try again.