Diffuse uterine leiomyomatosis is a benign and extremely rare condition in which the uterus is symmetrically enlarged as a result of the almost complete replacement of the myometrium by innumerable poorly defined, confluent leiomyomatous nodules.
Initial symptoms of the diffuse uterine leiomyomatosis usually are abdominal pain and abnormal uterine bleeding. Similar to uterine leiomyomas, patients with leiomyomatosis can present with menorrhagia, dysmenorrhea, abdominal pain, infertility, and pelvic pressure.
The exact etiology of these neoplasms is incompletely understood.
- is the method of choice
- the uterus appears diffusely enlarged shoiwng multiple innumerable ill defined leiomyomas without discrete margins
- 1. Coskun A, Ozdemir O, Vardar MA et-al. A case with diffuse uterine leiomyomatosis and review of the literature. Clin Exp Obstet Gynecol. 2008;35 (3): 227-30. - Pubmed citation
- 2. Mulvany NJ, Ostör AG, Ross I. Diffuse leiomyomatosis of the uterus. Histopathology. 1995;27 (2): 175-9. - Pubmed citation
- 3. Clement PB, Young RH. Diffuse leiomyomatosis of the uterus: a report of four cases. Int. J. Gynecol. Pathol. 1987;6 (4): 322-30. - Pubmed citation
- 4. Ueda H, Togashi K, Konishi I et-al. Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics. 1999;19 Spec No : S131-45. Radiographics (full text) - Pubmed citation