Eosinophilia myalgia syndrome

Last revised by Daniel J Bell on 16 Jan 2020

Eosinophilia myalgia syndrome (EMS) is a fatal neurological condition caused by ingestion of improperly manufactured L-tryptophan. Impurities and/or metabolites that block histamine degradation result in peripheral blood eosinophilia and myalgia. 

In the brain, cortical and basal ganglia atrophy with diffuse white matter abnormalities may be seen.

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