Ependymal rosettes (ependymoma)
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Ependymal rosetterosettes (ependymoma)
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Ependymal rosetterosettes correspondscorrespond to ana histologic architectural pattern that provides strong evidencevery characteristic of ependymomas, as tumour cells form structures similar to the lining of normal ventricles. It isThey are characterised by a halo or spoke-wheel arrangement of tumour cells surrounding an empty central tubule lumen.
They should not be confused with the far more common perivascular pseudorosette.
Differential diagnosis
It mustIn addition to perivascular pseudorosettes, an ependymal rosette should be differentiated from:
- Homer Wright rosette: central lumen filled with fiber-like processes
- Flexner-Wintersteiner rosette: central lumen contains small cytoplasmic extensions of the encircling cells
perivascular pseudorosette: cells surrounding a centrally native vessel- pineocytomatous and neurocytic rosettes: generally larger and more irregular in contour
-<p><strong>Ependymal rosette</strong> corresponds to an histologic architectural pattern that provides strong evidence of ependymal differentiation (<a href="/articles/ependymoma">ependymoma</a>). It is characterised by a halo or spoke-wheel arrangement of cells surrounding an empty tubule lumen.</p><h4>Differential diagnosis</h4><p>It must be differentiated from:</p><ul>- +<p><strong>Ependymal rosettes</strong> correspond to a histologic architectural pattern that very characteristic of <a href="/articles/ependymoma">ependymomas</a>, as tumour cells form structures similar to the lining of normal ventricles. They are characterised by a halo or spoke-wheel arrangement of tumour cells surrounding an empty central tubule lumen.</p><p>They should not be confused with the far more common <a href="/articles/perivascular-pseudorosettes-ependymoma">perivascular pseudorosette</a>. </p><ul><li> </li></ul><h4>Differential diagnosis</h4><p>In addition to perivascular pseudorosettes, an ependymal rosette should be differentiated from:</p><ul>
-<li>-<a href="/articles/perivascular-pseudorosette">perivascular pseudorosette</a>: cells surrounding a centrally native vessel </li>
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