Ependymal rosettes (ependymoma)

Changed by Yuranga Weerakkody, 3 Feb 2015

Updates to Article Attributes

Body was changed:

Ependymal rosette corresponds to an histologic architectural pattern that provides strong evidence of ependymal differentiation (ependymoma). It is characterised by a halo or spoke-wheel arrangement of cells surrounding an empty tubule lumen.

It must be differentiated from:

  • Homer Wright rosette: central lumen filled with fiber-like processes
  • Flexner-Wintersteiner rosette: central lumen contains small cytoplasmic extensions of the encircling cells
  • Perivascularperivascular pseudorosette: cells surrounding a centrally native vessel 
  • Pineocytomatouspineocytomatous and Neurocyticneurocytic rosettes:  generally larger and more irregular in contour
  • -<li>Homer Wright rosette: central lumen filled with fiber-like processes</li>
  • -<li>Flexner-Wintersteiner rosette: central lumen contains small cytoplasmic extensions of the encircling cells</li>
  • -<li>Perivascular pseudorosette: cells surrounding a centrally native vessel </li>
  • -<li>Pineocytomatous and Neurocytic rosettes:  generally larger and more irregular in contour</li>
  • +<li>
  • +<a title="Homer Wright rosettes" href="/articles/homer-wright-rosettes">Homer Wright rosette</a>: central lumen filled with fiber-like processes</li>
  • +<li>
  • +<a title="Flexner-Wintersteiner rosette" href="/articles/flexner-wintersteiner-rosette">Flexner-Wintersteiner rosette</a>: central lumen contains small cytoplasmic extensions of the encircling cells</li>
  • +<li>
  • +<a title="perivascular pseudorosette" href="/articles/perivascular-pseudorosette">perivascular pseudorosette</a>: cells surrounding a centrally native vessel </li>
  • +<li>pineocytomatous and neurocytic rosettes:  generally larger and more irregular in contour</li>
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