Revision 3 for 'Ependymal rosettes (ependymoma)'

All Revisions - View changeset

Ependymal rosette

Ependymal rosette corresponds to an histologic architectural pattern that provides strong evidence of ependymal differentiation (ependymoma). It is characterized by a halo or spoke-wheel arrangement of cells surrounding an empty tubule lumen.

It must be differentiated from:

  • Homer Wright rosette: central lumen filled with fiber-like processes
  • Flexner-Wintersteiner rosette: central lumen contains small cytoplasmic extensions of the encircling cells
  • Perivascular pseudorosette: cells surrounding a centrally native vessel 
  • Pineocytomatous and Neurocytic rosettes:  generally larger and more irregular in contour

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.