Citation, DOI, disclosures and article data
Citation:
Radswiki T, Jones J, Rasuli B, et al. Fetal anemia. Reference article, Radiopaedia.org (Accessed on 25 Apr 2024) https://doi.org/10.53347/rID-14573
Fetal anemia is a characterized by inadequate erythrocytes being delivered to the fetus and can result from many causes.
Etiology
Ultrasound
General sonographic features include:
Doppler
Fetal MRI
MRI can be used to detect fetal anemia 8 and some of its sequellae. T1 and T2 relaxation times of relevant areas e.g. the umbilical vein's blood allow for detection.
Treatment and prognosis
Intra-uterine transfusion via the umbilical vein can be successful in selected cases. The overall prognosis will depend on underlying conditions and associations.
-
1. Mari G, Adrignolo A, Abuhamad A et al. Diagnosis of Fetal Anemia with Doppler Ultrasound in the Pregnancy Complicated by Maternal Blood Group Immunization. Ultrasound Obstet Gynecol. 1995;5(6):400-5. doi:10.1046/j.1469-0705.1995.05060400.x - Pubmed
-
2. Christof, M.D. Sohn (Editor), Hans-Joachim Voigt (Editor), Klaus Vetter (Editor). Doppler Ultrasound in Gynecology and Obstetrics. (2004) ISBN: 1588902617 - Google Books
-
3. Mari G, Deter R, Carpenter R et al. Noninvasive Diagnosis by Doppler Ultrasonography of Fetal Anemia Due to Maternal Red-Cell Alloimmunization. Collaborative Group for Doppler Assessment of the Blood Velocity in Anemic Fetuses. N Engl J Med. 2000;342(1):9-14. doi:10.1056/NEJM200001063420102 - Pubmed
-
4. Delle Chiaie L, Buck G, Grab D, Terinde R. Prediction of Fetal Anemia with Doppler Measurement of the Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Maternal Blood Group Alloimmunization or Parvovirus B19 Infection. Ultrasound Obstet Gynecol. 2001;18(3):232-6. doi:10.1046/j.0960-7692.2001.00540.x - Pubmed
-
5. Oepkes D & Adama van Scheltema P. Intrauterine Fetal Transfusions in the Management of Fetal Anemia and Fetal Thrombocytopenia. Semin Fetal Neonatal Med. 2007;12(6):432-8. doi:10.1016/j.siny.2007.06.007 - Pubmed
-
6. Oepkes D, Seaward P, Vandenbussche F et al. Doppler Ultrasonography Versus Amniocentesis to Predict Fetal Anemia. N Engl J Med. 2006;355(2):156-64. doi:10.1056/NEJMoa052855 - Pubmed
-
7. Leung W, Oepkes D, Seaward G, Ryan G. Serial Sonographic Findings of Four Fetuses with Homozygous Alpha-Thalassemia-1 from 21 Weeks Onwards. Ultrasound Obstet Gynecol. 2002;19(1):56-9. doi:10.1046/j.0960-7692.2001.00498.x - Pubmed
-
8. Xu J, Duan A, Marini D et al. The Utility of MRI for Measuring Hematocrit in Fetal Anemia. Am J Obstet Gynecol. 2020;222(1):81.e1-81.e13. doi:10.1016/j.ajog.2019.07.016 - Pubmed
Promoted articles (advertising)