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Citation:
Radswiki T, Luong D, Sandhyala A, Fetal fibronectin test. Reference article, Radiopaedia.org (Accessed on 25 Apr 2024) https://doi.org/10.53347/rID-14747
The fetal fibronectin test (fFN) is a test that can be perfomed on a vaginal swab to estimate the risk of preterm labor.
Pathology
fFN is found at the interface of the chorion and the decidua (between the fetal sack and the uterine lining). It can be thought of as an adhesive or "biological glue" that binds the fetal sac to the uterine lining.
While a negative test is generally useful to rule out preterm labor (high negative predictive value), a positive test is not useful to predict the likelihood (low positive predictive value).
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2. Skoll A, St louis P, Amiri N et-al. The evaluation of the fetal fibronectin test for prediction of preterm delivery in symptomatic patients. J Obstet Gynaecol Can. 2006;28 (3): 206-13. - Pubmed citation
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3. Shennan A, Jones G, Hawken J et-al. Fetal fibronectin test predicts delivery before 30 weeks of gestation in high risk women, but increases anxiety. BJOG. 2005;112 (3): 293-8. doi:10.1111/j.1471-0528.2004.00420.x - Pubmed citation
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