Galaxy sign (lungs)
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Galaxy sign (lungs)
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The so-called galaxy sign, initially described as the sarcoid galaxy, represents a coalescent granuloma seen in a minority of patients with pulmonary sarcoidosis 1. The same appearance can be seen in tuberculosis 2,3. In other words, it represents a mass-like region composed of numerous smaller granulomas. The appearance of a central core with peripheral nodules is reminiscent of a globular cluster galaxy.
Central cavitation does occur and the lesions may be surrounded by ground-glass opacity. The latter is thought to represent extensive interstitial sarcoid granulomas below the resolution of HRCT rather than alveolitis or haemorrhage 1.
-<p>The so-called <strong>galaxy sign</strong>, initially described as the <strong>sarcoid galaxy</strong>, represents a coalescent granuloma seen in a minority of patients with <a href="/articles/sarcoidosis-pulmonary-manifestations">pulmonary sarcoidosis</a> <sup>1</sup>. The same appearance can be seen in <a href="/articles/tuberculosis-pulmonary-manifestations">tuberculosis</a> <sup>2,3</sup>. In other words, it represents a mass-like region composed of numerous smaller granulomas. The appearance of a central core with peripheral nodules is reminiscent of a globular cluster galaxy.</p><p>Central cavitation does occur and the lesions may be surrounded by <a href="/articles/ground-glass-opacification">ground-glass opacity</a>. The latter is thought to represent extensive interstitial sarcoid granulomas below the resolution of HRCT rather than alveolitis or haemorrhage <sup>1</sup>. </p>- +<p>The so-called <strong>galaxy sign</strong>, initially described as the <strong>sarcoid galaxy</strong>, represents a coalescent granuloma seen in a minority of patients with <a href="/articles/sarcoidosis-thoracic-manifestations-2">pulmonary sarcoidosis</a> <sup>1</sup>. The same appearance can be seen in <a href="/articles/tuberculosis-pulmonary-manifestations-1">tuberculosis</a> <sup>2,3</sup>. In other words, it represents a mass-like region composed of numerous smaller granulomas. The appearance of a central core with peripheral nodules is reminiscent of a globular cluster galaxy.</p><p>Central cavitation does occur and the lesions may be surrounded by <a href="/articles/ground-glass-opacification">ground-glass opacity</a>. The latter is thought to represent extensive interstitial sarcoid granulomas below the resolution of HRCT rather than alveolitis or haemorrhage <sup>1</sup>. </p>
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