Gallbladder agenesis
Updates to Article Attributes
Body
was changed:
Agenesis of the gallbladder is a rare congenital anomaly.
Epidemiology
The
-
overall incidence is estimated <0.1% (range 0.04-0.1%)
. There is strong -
gender:
-
reported 3:1 female predominance
present among theof symptomatic cases. - equivalent gender distribution in autopsy cases
-
reported 3:1 female predominance
Clinical presentation
Most patients with agenesis of the gallbladder are asymptomatic. Although some patients may present with signs and symptoms of gallbladder disease and ultrasound may suggest findings consistent with chronic cholecystitis (shrunken gallbladder). Jaundice may be present with a dilated common bile duct. There is a high incidence of choledocholithiasis.
Pathology
The exact aetiology is unknown, however it is thought to result either from failure of the cystic bud to form or from lack of vacuolation. Several cases of familial gallbladder agenesis have also been reported, suggesting a hereditary basis of the anomaly.
Associations
Gallbladder agenesis is associated with several other anomalies:
-<p><strong>Agenesis of the gallbladder</strong> is a rare congenital anomaly.</p><h4>Epidemiology</h4><p>The incidence is <0.1% (range 0.04-0.1%). There is strong female predominance present among the symptomatic cases.</p><h4>Clinical presentation</h4><p>Most patients with agenesis of the gallbladder are asymptomatic. Although some patients may present with signs and symptoms of gallbladder disease and ultrasound may suggest findings consistent with <a href="/articles/chronic-cholecystitis">chronic cholecystitis</a> (shrunken gallbladder). <a href="/articles/jaundice">Jaundice</a> may be present with a dilated <a href="/articles/common-bile-duct">common bile duct</a>. There is a high incidence of <a href="/articles/choledocholithiasis">choledocholithiasis</a>.</p><h4>Pathology</h4><p>The exact aetiology is unknown, however it is thought to result either from failure of the cystic bud to form or from lack of vacuolation. Several cases of familial gallbladder agenesis have also been reported, suggesting a hereditary basis of the anomaly.</p><h5>Associations</h5><p>Gallbladder agenesis is associated with several other anomalies:</p><ul>- +<p><strong>Agenesis of the gallbladder</strong> is a rare congenital anomaly.</p><h4>Epidemiology</h4><ul>
- +<li>overall incidence is estimated <0.1% (range 0.04-0.1%)</li>
- +<li>gender: <ul>
- +<li>reported 3:1 female predominance of symptomatic cases</li>
- +<li>equivalent gender distribution in autopsy cases</li>
- +</ul>
- +</li>
- +</ul><h4>Clinical presentation</h4><p>Most patients with agenesis of the gallbladder are asymptomatic. Although some patients may present with signs and symptoms of gallbladder disease and ultrasound may suggest findings consistent with <a href="/articles/chronic-cholecystitis">chronic cholecystitis</a> (shrunken gallbladder). <a href="/articles/jaundice">Jaundice</a> may be present with a dilated <a href="/articles/common-bile-duct">common bile duct</a>. There is a high incidence of <a href="/articles/choledocholithiasis">choledocholithiasis</a>.</p><h4>Pathology</h4><p>The exact aetiology is unknown, however it is thought to result either from failure of the cystic bud to form or from lack of vacuolation. Several cases of familial gallbladder agenesis have also been reported, suggesting a hereditary basis of the anomaly.</p><h5>Associations</h5><p>Gallbladder agenesis is associated with several other anomalies:</p><ul>
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