Revision 3 for 'Gallbladder agenesis'

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Gallbladder agenesis

Agenesis of gallbladder is a rare congenital anomaly.

Epidemiology

Incidence varies from 0.04-0.1%.There is strong female predominace present among the symptomatic cases.

Pathology

Exact cause is not known, however it is thought to result either from failure of cystic bud to form or from lack of vacuolation. Several cases of familial gallbladder agenesis have also been reported, suggesting a heriditary basis of the anomaly.

Clinical presentation

Most of the patients with agenesis of the gallbladder are asymptomatic. Although some patients may present with signs and symptoms of gallbladder disease and USG may suggest small shrunken gallbladder consistant with chronic cholecystitis. Jaundice may be present with dilated CBD. There is high incidence of choledocholithiasis.

Agenesis of gallbladder is associated with several other anomalies including

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