Gastric duplication cyst

Last revised by Nicolas Linder on 19 Jul 2023

Gastric duplication cysts are rare congenital foregut duplication cysts affecting the stomach. Gastrointestinal tract duplication cysts (GTDCs) most commonly affect the ileum, followed by the esophagus, large bowel, and jejunum; gastric location accounts for less than 10% of all gastrointestinal duplications.

A review of four large series comprising 281 cases of gastrointestinal tract duplication cysts, demonstrated that duplications of the stomach constituted about 7% 1.

Clinical manifestations are dependent on location, size, and mucosal pattern. Symptoms, if present, usually appear before one year of age 2:

  • upper abdominal obstruction

  • abdominal pain

  • palpable mass

By definition, the gastric duplication has some defining characteristics as a well-developed layer of smooth muscle and an epithelial lining representing some part of the alimentary tract, and are attached to some part of the stomach sharing a common muscle wall and blood supply 3.

Duplication cysts may also contain heterotopic tissue which can include:

The majority are non-communicating, spherical cysts and the greater curve is the most common site of its occurrence 1.

An abdominal plain radiograph can demonstrate a soft tissue mass displacing air-filled bowel loops. There can be occasional calcification in the cysts wall 6.

A barium study may show a filling defect due to extrinsic compression from these cystic masses.

Sonography plays an important role in these patients and many authors have demonstrated that the combination of an echogenic inner mucosal layer and hypoechoic outer muscular layer are highly suggestive of a gastrointestinal tract duplication cyst 4.

CT scans will show a fluid-attenuation cystic mass in close contact with the stomach. 

Magnetic resonance demonstrates features common to cysts with typical signal characteristics being:

  • T1: low signal         

  • T2: high signal

  • T1 C+ (Gd): the cyst wall can show slight enhancement 6

Recognized complications include:

The above complications are especially likely if duplication cysts contain ectopic gastric mucosa (which occurs in 20-50% of duplications) or ectopic pancreatic tissue 6.

General imaging differential considerations include:

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