Gastric polyps are uncommon findings, even on endoscopy where they are encountered in only 2-6% of patients.
Pathology
There are a number of gastric polyp subtypes 1-3:
- non-neoplastic polyps
- hyperplastic polyps
- virtually no malignant potential
- typically small (<1 cm), multiple, and sessile
- associated with H. pylori infection so most of them regress after treatment of H. pylori infection
- hamartomatous polyps
- inflammatory fibroid polyp
- hyperplastic polyps
- neoplastic polyps
-
fundic gland polyp (most common)
- may arise sporadically or as part of familial adenomatous polyposis (FAP)
- increase in incidence by proton pump inhibitors
- in some texts, these are grouped with hyperplastic polyps
- adenomatous polyp: precursor lesion to gastric adenocarcinoma
- polypoid gastric adenocarcinoma
-
fundic gland polyp (most common)
There are a variety of lesions that may have polypoid-growth, such as gastric carcinoid, gastrointestinal stromal tumor (GIST), lymphoma, leiomyoma, etc.