Column of Goll
The columns of Goll, also known as the gracile fasciculus or fasciculus gracilis, represent the medial portions of the dorsal columns and carry input from below and including T7 1.
First-order neurons from peripheral receptors enter the spinal cord via the posterior roots, and unlike first-order neurons from the spinothalamic tract, do not synapse in the posterior posterior grey horn of the cord. Thus, these first-order neurons form the gracile fasciculus of the dorsal columns if input was from T7 or below.
Unlike fibers of the spinothalamic tract, these first-order neurons in the gracile fasciculus continue to ascend without decussation. This ipsilateral ascension continues until the medulla oblongata of the brainstem.
Upon reaching the gracile nucleus of the caudal medulla oblongata these first-order neurons terminate and synapse with second-order neurons. These second-order neurons then decussate to the contralateral side, known as the internal arcuate fibers during this decussation. These decussated neurons continue to ascend as part of the medial lemniscus where they terminate in the ventral posterior nucleus of the thalamus. Here, they synapse with third-order neurons. It is these neurons that finally project to the primary somatosensory area on the ipsilateral side of the cerebral cortex.
- intramedullary spinal tumor
- spinal cord injury
- Brown-Séquard syndrome
- transverse myelitis
- multiple sclerosis
- subacute combined degeneration of the cord
- nitrous oxide toxicity
- copper deficiency myeloneuropathy
- neurosyphilis (tabes dorsalis)
- HIV vacuolar myelopathy
History and etymology
Named after Friedrich Goll (1829-1903), a Swiss anatomist (1776-1847) 2.
- fasiculus cuneatus (column of Burdach)