A ground-glass density nodule (GGN) is a circumscribed area of increased pulmonary attenuation with preservation of the bronchial and vascular margins. A GGN can be:
Although encountered regularly, the incidence of cancer in these nodules has been reported as high as 63% (for partly solid nodules, in one study). Histologically these may represent:
See also
- 1. Feely MA, Hartman TE. Inappropriate application of nodule management guidelines in radiologist reports before and after revision of exclusion criteria. AJR Am J Roentgenol. 2011;196 (5): 1115-9. doi:10.2214/AJR.10.5141 - Pubmed citation
- 2. Henschke CI, Yankelevitz DF, Mirtcheva R et-al. CT screening for lung cancer: frequency and significance of part-solid and nonsolid nodules. AJR Am J Roentgenol. 2002;178 (5): 1053-7. AJR Am J Roentgenol (citation) - Pubmed citation
- 3. Macmahon H, Austin JH, Gamsu G et-al. Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology. 2005;237 (2): 395-400. Radiology (full text) - doi:10.1148/radiol.2372041887 - Pubmed citation
- 4. Takahashi S, Tanaka N, Okimoto T et-al. Long term follow-up for small pure ground-glass nodules: implications of determining an optimum follow-up period and high-resolution CT findings to predict the growth of nodules. Jpn J Radiol. 2012;30 (3): 206-17. Jpn J Radiol (full text) - doi:10.1007/s11604-011-0033-8 - Pubmed citation
- 5. Park CM, Goo JM, Kim TJ et-al. Pulmonary nodular ground-glass opacities in patients with extrapulmonary cancers: what is their clinical significance and how can we determine whether they are malignant or benign lesions?. Chest. 2008;133 (6): 1402-9. doi:10.1378/chest.07-2568 - Pubmed citation
- 6. Kim SB, Lee S, Koh MJ et-al. Ground-glass opacity in lung metastasis from breast cancer: a case report. Tuberc Respir Dis (Seoul). 2013;74 (1): 32-6. doi:10.4046/trd.2013.74.1.32 - Free text at pubmed - Pubmed citation
- 7. Kobayashi Y, Mitsudomi T. Management of ground-glass opacities: should all pulmonary lesions with ground-glass opacity be surgically resected?. (2013) Translational lung cancer research. 2 (5): 354-63. doi:10.3978/j.issn.2218-6751.2013.09.03 - Pubmed
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