Hepatoblastoma histological classification

Last revised by Daniel J Bell on 26 Nov 2019

Although hepatoblastomas can be histologically classified into a variety of subtypes, it is important to remember that with the possible exception of small cell undifferentiated subtype, prognosis is independent of histology when adjusted for stage gender and age 1.

  • major categories
    • epithelial
      • fetal, well differentiated
      • embryonal
      • macrotrabecular
    • mixed
    • small cell undifferentiated
    • rhabdoid
  • minor categories
    • cholangioblastic (ductal)
    • keratinizing squamous epithelium
    • intestinal glandular epithelium
    • teratoid (neuroid-melanocytic)
    • rhabdomyoblastic
    • chondroid
    • osteoid

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