Citation, DOI and article data
Hepatomegaly refers to an increase in size or enlargement of the liver.
Hepatomegaly can result from a vast range of pathology including, but not limited to, the following:
- malignancy/cellular infiltrate
- acquired hepatic conditions
- acquired non-hepatic conditions
- congenital anomalies
Assessment of liver size is commonly made on ultrasound or CT, although gross hepatomegaly may be apparent on abdominal radiograph.
For the adult liver:
- midclavicular line averages 10-12.5 cm in craniocaudal length 2
- a liver that is longer than 15.5-16 cm in the midclavicular line (MCL) is considered enlarged
- average transverse diameter is 20-23 cm at the level of the upper pole of the right kidney 2
In practice, however, assessment is often subjective.
Features that support hepatomegaly include 1:
- extension of the right lobe inferior to the lower pole of the right kidney
- rounding of the hepatic inferior border
- 1. Brant WE, Helms CA. Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins. (2007) ISBN:0781761352. Read it at Google Books - Find it at Amazon
- 2. Kennedy PA, Madding GF. Surgical anatomy of the liver. Surg. Clin. North Am. 1977;57 (2): 233-44. Pubmed citation
- 3. Dähnert W. Radiology Review Manual. (2011) ISBN: 9781609139438
- 4. Wolfgang Dähnert. Radiology Review Manual. (2011) ISBN: 9781609139438