Hepatosplenomegaly

Last revised by Rohit Sharma on 26 Jun 2022

Hepatosplenomegaly is simply the simultaneous presence of a pathologically-enlarged liver (hepatomegaly) and spleen (splenomegaly).

Pathology

Etiology
Infection

Many infections can produce a mild concurrent enlargement of the liver and spleen. This list is by no means exhaustive.

Malignancy
Hematological
Storage diseases/metabolic/infiltrative disorders
Connective tissue disorders
Others

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