Homer Wright rosettes
Homer Wright rosettes are differentiated tumor cells grouped around a central region containing neuropil (therefore its association with tumors of neuronal origin).
Examples of tumors where these pseudorosettes can be seen include:
- medulloblastoma (the presence of Homer Wright rosettes in a posterior fossa tumor is nearly pathognomonic for medulloblastoma)
- primitive neuroectodermal tumors (PNETs)
- olfactory neuroblastoma
History and etymology
Homer Wright rosettes are named after James Homer Wright (1869–1928), Massachusetts (USA), developer of the Wright stain.