Interstitial cystitis

Interstitial cystitis (or painful bladder syndrome) refers to an inflammatory condition affecting the bladder. It is usually classified as urinary bladder pain and irritative symptoms of more than 6 months' duration. It usually represents a diagnosis of exclusion. Traditionally, it has been defined as a chronic sterile inflammatory disease of the bladder of unknown etiology 3.


It tends to commonly occur in young to middle-aged women 1.


Its exact etiology is uncertain. Proposed theories of pathogenesis are wide and include chronic or subclinical infection, autoimmune phenomena, neurogenic inflammation or bladder urothelial defects.

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Article information

rID: 64817
System: Urogenital
Synonyms or Alternate Spellings:
  • Painful bladder syndrome

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