Interstitial cystitis (or painful bladder syndrome) refers to an inflammatory condition affecting the bladder. It is usually classified as urinary bladder pain and irritative symptoms of more than 6 months' duration. It usually represents a diagnosis of exclusion. Traditionally, it has been defined as a chronic sterile inflammatory disease of the bladder of unknown etiology 3.
It tends to commonly occur in young to middle-aged women 1.
Its exact etiology is uncertain. Proposed theories of pathogenesis are wide and include chronic or subclinical infection, autoimmune phenomena, neurogenic inflammation or bladder urothelial defects.
- 1. Grover S, Srivastava A, Lee R, Tewari AK, Te AE. Role of inflammation in bladder function and interstitial cystitis. (2011) Therapeutic advances in urology. 3 (1): 19-33. doi:10.1177/1756287211398255 - Pubmed
- 2. Dasgupta J, Tincello DG. Interstitial cystitis/bladder pain syndrome: an update. (2009) Maturitas. 64 (4): 212-7. doi:10.1016/j.maturitas.2009.09.016 - Pubmed
- 3. Kelada E, Jones A. Interstitial cystitis. (2007) Archives of gynecology and obstetrics. 275 (4): 223-9. doi:10.1007/s00404-006-0247-7 - Pubmed