Intramural bowel gas

Dr Owen Kang and Dr Jeremy Jones et al.

Intramural bowel gas, also known as pneumatosis intestinalis, refers to the clinical or radiological finding of gas within the wall of the bowel.

There are different terminologies in the medical literature, such as pneumatosis intestinalis, pneumatosis coli, and pneumatosis cystoides intestinalis. Pneumatosis coli is used when only the colic wall is involved and is generally an incidental finding in asymptomatic patients. Pneumatosis cystoides intestinalis is descriptive for multiple gaseous cysts along the bowel wall.

Intramural gas can be seen in intestinal ischemia and eventually bowel infarction. This is the most concerning etiology for intramural gas.

Gas in the bowel wall in the neonatal period, whatever its shape, is diagnostic of necrotizing enterocolitis.

Asymptomatic pneumatosis intestinalis may result from a variety of interrelated contributing factors including:

  • mucosal integrity
  • intraluminal pressure
  • bacterial flora
  • intraluminal gas

Gas tracks along the bowel wall, appearing as either linear, which are usually submucosal, or rounded cystic "bubbly" collections, which are usually subserosal 1. Where they join, they may outline the circumferenial margin of the bowel, creating rings.

Gas in the bowel wall is most easily identified with CT and plain radiography, but ultrasound and MRI can be usefully in pediatric patients where there is a desire to avoid radiation.

Other imaging findings help differentiate sinister causes from benign causes, such as 4:

The presence of pneumomediastinum favors a benign cause 1.

  • bowel ischemia and infarction
  • infection
  • inflammatory bowel disease
  • medication-induced
    • chemotherapy
    • steroid use
  • autoimmune disease and immunosuppression
  • connective tissue disorders
  • primary pneumatosis
  • pulmonary disease
  • idiopathic
  • iatrogenic
    • post endoscopy / colonoscopy
    • post operative
    • post enteric tube
    • CT colonography
  • pseudopneumatosis (mimics) include:
    • gas trapped between bowel wall and luminal contents
    • gas trapped by opposing mucosal folds
    • gas bubbles adherent to bowel wall

From a clinical perspective, it is essential not to confuse the incidental imaging finding of asymptomatic pneumatosis with symptomatic colonic perforation because the treatment is significantly different 2.

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Article information

rID: 6168
Section: Signs
Synonyms or Alternate Spellings:
  • Pneumatosis intestinalis
  • Gas within the bowel wall

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Cases and figures

  • Case 1: necrotizing enterocolitis
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  • Case 2: virtual endoscopic view showing gas pocket
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  • Intramural gas
    Case 4
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  • Case 3: in mid jejunum with concurrent portal venous gas
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  • Case 5
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  • Case 6
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  • Case 7: in NEC
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  • Case 8: obstructing colon cancer
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  • Case 9: following jejunostomy
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  • Case 10: SMA oclusion
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  • Case 10: SMA occlusion
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  • Case 11: pneumatosis coli
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