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Iris (eye)

Dr Daniel J Bell ◉ et al.

The iris (plural: irises or irides) is a pigmented muscular structure which modifies the amount of light entering the eye, by controlling the size of the pupil, its central aperture.

On this page:

Article:

Summary
Gross anatomy
Arterial supply
Venous drainage
Lymphatic drainage
Histology
Related pathology
Related articles
References

Summary

location: between the anterior and posterior chambers of the globe
function: controls the amount of light entering the eye
blood supply and drainage: anterior ciliary vessels
relations
- anterior: anterior chamber
- posterior: posterior chamber
- medial: pupil
- lateral: ciliary body

Gross anatomy

Location

The iris forms the anterior most component of the uvea, which is the vascular layer of the globe. Posteriorly the ciliary body and, most posteriorly, the choroid complete the uvea.

The iris is a ring-shaped structure, secured to the inner aspect of the ciliary body, which encircles it. The iris has a central aperture, the pupil, the variable diameter of which modifies the quantity of light reaching into the eye.

Most of the iris comprises vascularized stroma with scattered melanocytes. The coloration of the iris varies with its pigment content. At birth the iris is blue, due to absence of pigment. As the infant grows, pigment cells may proliferate, resulting in darker iridal colors.

Function

The iris has radially-arranged dilator pupillae muscles, and concentrically-arranged sphincter pupillae muscles. These muscles dilate and constrict the pupil, in response to sympathetic and parasympathetic nerve impulses, from the long ciliary nerve and oculomotor nerve (III), respectively.

Relations

anterior: anterior chamber and cornea
posterior: posterior chamber and lens
- in vivo, the margin of the pupil is in contact with the lens
lateral: ciliary body
medial: pupil

Arterial supply

anterior ciliary arteries

Venous drainage

anterior ciliary veins

Lymphatic drainage

there is no lymphatic drainage of the globe or its parts

Histology

Most of the iris comprises markedly vascularized loosely-compacted stroma, with melanocytes dispersed throughout the tissue. The anterior aspect of the iris is uneven, formed by an incomplete layer of fibroblasts and melanocytes. Conversely its posterior aspect is fairly even, formed by an epithelial layer, which originates embryologically in continuity with the double layer of cuboidal epithelium lining the ciliary body.

The superficial layer of this iridal epithelium is so heavily pigmented (cf. non-pigmented in the ciliary body) that the cells can no longer be distinguished from one another. The deeper layer consists of radially-oriented myoepithelial cells which are only lightly colored and constitute the dilator pupillae muscle.

The constrictor pupillae muscle is formed by intrastromal muscle fibers located near the inner margin of the iris, which are laid down concentrically.

The coloration of the iris relates to the quantity of pigment in the anterior stroma, which shows individual variation across the population. The melanocytes of the posterior epithelium exhibit little variation in pigmentation between individuals. People lacking stromal pigment have blue eyes, conversely those whose stroma is hyperpigmented have brown eyes.

Related pathology

References

Anatomy: Head and neck

Article information

rID: 65125

System: Central Nervous System, Head & Neck

Section: Anatomy

Tag: cases, reference needed

Synonyms or Alternate Spellings:

Pupil
Irises
Irides

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