John Cunningham virus
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John Cunningham (JC) virus is an ubiquitous double-stranded DNA virus member of the polyomaviridae family 1. It is the aetiological agent of the progressive multifocal leukoencephalopathy (PML).
Epidemiology
It was reported that ~70% of adults have been exposed to this virus, however no clinical syndrome has been associated with this acquisition 1.
History and etymology
The virus was first described by Åström et al. in 1958 2, and it was first isolated in 1971 by Padgett et al. This latter group assigned the name of the patient to the virus 3.
-<p><strong>John Cunningham (JC) virus</strong> is an ubiquitous double-stranded DNA virus member of the polyomaviridae family <sup>1</sup>. It is the aetiological agent of the <a href="/articles/progressive-multifocal-leukoencephalopathy">progressive multifocal leukoencephalopathy (PML)</a>.</p><h4>Epidemiology</h4><p>It was reported that ~70% of adults have been exposed to this virus, however no clinical syndrome has been associated with this acquisition <sup>1</sup>. </p><h4>History and etymology </h4><p>The virus was first described by <strong>Åström</strong> et al. in 1958 <sup>2</sup>, and it was first isolated in 1971 by <strong>Padgett</strong> et al. <sup>3</sup>.</p>- +<p><strong>John Cunningham (JC) virus</strong> is an ubiquitous double-stranded DNA virus member of the polyomaviridae family <sup>1</sup>. It is the aetiological agent of the <a href="/articles/progressive-multifocal-leukoencephalopathy">progressive multifocal leukoencephalopathy (PML)</a>.</p><h4>Epidemiology</h4><p>It was reported that ~70% of adults have been exposed to this virus, however no clinical syndrome has been associated with this acquisition <sup>1</sup>. </p><h4>History and etymology </h4><p>The virus was first described by <strong>Åström</strong> et al. in 1958 <sup>2</sup>, and it was first isolated in 1971 by <strong>Padgett</strong> et al. This latter group assigned the name of the patient to the virus <sup>3</sup>. </p>
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