Revision 5 for 'John Cunningham virus'

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John Cunningham virus

John Cunningham (JC) virus is an ubiquitous double-stranded DNA virus, member of the polyomaviridae family 1. It is the etiological agent of the progressive multifocal leukoencephalopathy (PML).

Epidemiology

It was reported that ~70% of adults have been exposed to this virus, however no clinical syndrome has been associated with this acquisition 1

History and etymology 

The virus was first described by Åström et al. in 1958 2, and it was first isolated in 1971 by Padgett et al. 3.

 

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