John Cunningham virus
John Cunningham (JC) virus is an ubiquitous double-stranded DNA virus member of the polyomaviridae family 1. It is the etiological agent of the progressive multifocal leukoencephalopathy (PML).
It was reported that ~70% of adults have been exposed to this virus, however no clinical syndrome has been associated with this acquisition 1.
History and etymology
The virus was first described by Åström et al. in 1958 2, and it was first isolated in 1971 by Padgett et al. 3.