Revision 7 for 'John Cunningham virus'

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John Cunningham virus

John Cunningham (JC) virus is an ubiquitous double-stranded DNA virus member of the polyomaviridae family 1. It is the etiological agent of the progressive multifocal leukoencephalopathy (PML).


It was reported that ~70% of adults have been exposed to this virus, however no clinical syndrome has been associated with this acquisition 1

History and etymology 

The virus was first described by Åström et al. in 1958 2, and it was first isolated in 1971 by Padgett et al. This latter group assigned the name of the patient to the virus 3

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