Juxta-cortical chondrosarcoma

A.Prof Frank Gaillard et al.

Juxta-cortical chondrosarcomas, also known as periosteal chondrosarcomas, are indistinguishable histologically from conventional medullary chondrosarcomas and are therefore graded into low, intermediate or high-grade tumors (see chondrosarcoma grading).

Typically it occurs in adults in their 3rd and 4th decades and is slightly more frequent in males.

Unlike conventional chondrosarcomas, they arise from the surface of the bone, lifting the periosteum over themselves as a fibrous pseudocapsule. The underlying cortex is usually thickened or may be eroded, however, extension into the medullary cavity is not usual. Where the periosteum is lifted a Codman triangle may be seen. In addition to the usual chondroid matrix, metaplastic ossification is also common.

They typically arise from long bones, with a predilection for the posterior aspect of the distal femur.

Bone tumours

The differential diagnosis for bone tumors is dependent on the age of the patient, with a very different set of differentials for the pediatric patient.

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Article information

rID: 6195
Synonyms or Alternate Spellings:
  • Periosteal chondrosarcoma
  • Juxta-cortical chondrosarcomas
  • Periosteal chondrosarcomas

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Cases and figures

  • Case 1: T2
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