Liver Imaging Reporting and Data System (LI-RADS) is a standardized terminology and classification system for imaging findings in liver lesions. A liver lesion's LI-RADS score indicates its relative risk for hepatocellular carcinoma (HCC).
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Usage
The classification system is meant to be used in livers with risk factors for HCC (e.g. cirrhotic livers, chronic HBV without cirrhosis). LI-RADS is not meant to be used in patients <18 years old, those with cirrhosis due to congenital hepatic fibrosis, and those with cirrhosis due to vascular disorders (e.g. Budd-Chiari syndrome).
It has been proposed to decrease the variability in the interpretation of liver lesions in at-risk patients. Standardization also helps interpret therapeutic performance. The scoring system also helps communicate more clearly to non-hepatologists the degree of suspicion attached to liver lesions in their patients.
Classification
The four LI-RADS classification algorithms are 1:
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LI-RADS Ultrasound Surveillance
for surveillance of HCC
using unenhanced ultrasound
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for diagnosis of HCC
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for diagnosis and staging of HCC
using CT or MRI with extracellular contrast agents, or MRI with hepatobiliary contrast agents
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CT/MRI Treatment Response LI-RADS
for assessing response of HCC to locoregional treatment
using CT or MRI with extracellular contrast agents, or MRI with hepatobiliary contrast agents
History and etymology
Initial versions of LI-RADS was created in 2006 and modelled after the Breast imaging-reporting and data system (BI-RADS) by the American College of Radiology. It has since undergone multiple iterations, receiving contributions from a multidisciplinary international consortium of clinicians and academics.
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