Liquefactive necrosis
Last revised by Daniel J Bell on 21 Apr 2021
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Bell D, Glick Y, Liquefactive necrosis. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-53996
Permalink:
rID:
53996
Article created:
18 Jun 2017,
Yuranga Weerakkody ◉
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
21 Apr 2021,
Daniel J Bell ◉
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
3 times, by
3 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- Colliquative necrosis
Liquefactive necrosis is a form of necrosis where there is transformation of the tissue into a liquid viscous mass.
Pathology
In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes leading to a soft, circumscribed lesion which can consist of fluid with remains of necrotic tissue or pus.
It is commonly associated with infection, dependant on the site of involvement.
Location
Reported organs in which liquefactive necrosis is a recognized phenomenon include:
-
lung
- a lung abscess if considered a form of liquefactive necrosis
- brain 3
- spleen 2
- pancreas 1
References
- 1. Burrell M, Gold JA, Simeone J, Taylor K, Dobbins J. Liquefactive necrosis of the pancreas: the pancreatic sac. Radiology. 135 (1): 157-60. doi:10.1148/radiology.135.1.7360954 - Pubmed
- 2. Downer WR, Peterson MS. Massive splenic infarction and liquefactive necrosis complicating polycythemia vera. AJR. American journal of roentgenology. 161 (1): 79-80. doi:10.2214/ajr.161.1.8517327 - Pubmed
- 3. Estes ML, Rorke LB. Liquefactive necrosis in Coxsackie B encephalitis. Archives of pathology & laboratory medicine. 110 (11): 1090-2. Pubmed
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