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Malignant phyllodes tumor

Dr Francis Deng and Radswiki et al.

Malignant phyllodes tumor of the breast accounts for up to a quarter of the phyllodes tumors.

Please, refer to the main article on phyllodes tumors for a general discussion.

On this page:

Article:

Pathology
Radiographic features
Treatment and prognosis
Related articles
References

Pathology

It is generally thought that it is the stromal component that becomes malignant ⁴. This may account for their haematogenous metastatic pattern.

Radiographic features

A substantial overlap in the imaging characteristics has been reported between benign and malignant phyllodes tumors. A tumor diameter of 3 cm or greater has been generally reported to be associated with a higher likelihood of malignancy ³.

Treatment and prognosis

Fewer than 20% of the malignant tumors metastasize. When metastatic disease does occur, the metastases usually spread haematogenously to the lungs, pleura, or bone. Surgery is the mainstay of treatment as they are not proven to be sensitive to radiotherapy or chemotherapy. Because lymphatic metastasis is rare, axillary nodal surgery is not indicated.

References

Breast imaging and pathology

Article information

rID: 15265

System: Breast

Tag: cases, cases

Synonyms or Alternate Spellings:

Malignant phyllodes tumours
Malignant phyllodes tumor
Malignant phyllodes tumors
Malignant phyllodes tumours of the breast
Malignant cystosarcoma phyllodes

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