Malignant transformation
Updates to Article Attributes
Body
was changed:
Malignant transformation is the term given to the process whereby either normal tissues, metaplastic, or a benign neoplasmneoplastic tissue, becomes a cancer. The process usually occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype. The genetic steps are gradually being elucidated 1.
-<p><strong>Malignant transformation</strong> is the term given to the process whereby either normal tissues or a benign neoplasm becomes a <a title="Cancer" href="/articles/cancer">cancer</a>. The process occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype.</p><p> </p><p> </p>- +<p><strong>Malignant transformation</strong> is the term given to the process whereby either normal, metaplastic, or benign neoplastic tissue, becomes a <a href="/articles/cancer">cancer</a>. The process usually occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype. The genetic steps are gradually being elucidated <sup>1</sup>.</p>
References changed:
- 1. Pütz SM, Vogiatzi F, Stiewe T, Sickmann A. Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE. (2010) Molecular cancer. 9: 254. <a href="https://doi.org/10.1186/1476-4598-9-254">doi:10.1186/1476-4598-9-254</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/20860785">Pubmed</a> <span class="ref_v4"></span>
Sections changed:
- Pathology
Systems changed:
- Oncology