Mediastinal lipomatosis

Last revised by Yaïr Glick on 24 Dec 2023

Mediastinal lipomatosis refers to a condition where there is deposition of a large amount of mature adipose tissue in the mediastinum. It is a relatively common benign cause of mediastinal widening.  

Mediastinal lipomatosis is the result of increased deposition of normal unencapsulated fat 1

It is most common in the upper mediastinum 2.

Seen as regions of homogeneous unencapsulated fat attenuating involving the mediastinum, sharply outlining vessels and lymph nodes 2.

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