Mixed connective tissue disease (pulmonary manifestations)

Last revised by Yuranga Weerakkody on 2 Oct 2023

Pulmonary manifestations of mixed connective tissue disease can be seen in a wide range (20-85%) of those of mixed connective tissue disease. It can have multiple manifestations. 

More commonly described features include:

Other rare presentations include:

Individual imaging features are nonspecific on their own.

A prerequisite for the diagnosis of mixed connective tissue disease is the presence, in the serum, of high titers of antibodies against uridine-rich RNA-small nuclear ribonucleoprotein (snRNP) 2.

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