Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Knipe H, Skandhan A, et al. Myxoinflammatory fibroblastic sarcoma. Reference article, Radiopaedia.org (Accessed on 16 Apr 2024) https://doi.org/10.53347/rID-41951
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Henry Knipe's current disclosures
Myxoinflammatory fibroblastic sarcoma is an uncommon intermediate-grade fibroblastic/myofibroblastic tumour.
When occurring the finger, the term acral myxoinflammatory fibroblastic sarcoma is used.
It typically affects adults.
The patient may present with painless swelling.
This tumour is microscopically characterised by solid nests of atypical spindle and epithelioid cells in a myxoid stroma accompanied by dense inflammatory infiltrates.
Location
It most commonly occurs in the distant extremities. The fingers are a particularly common site of occurrence.
MRI
MRI features can have some variation 3. Usually seen as a poorly circumscribed mass involving an underlying tendon sheath in the distal extremities. Can often have a multinodular appearance.
Treatment and prognosis
It generally carries relatively good prognosis with a long life expectancy although frequent local recurrence can occur 4.
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History and etymology
It was first described in 1998 by Meis-Kindblom and Montgomery et al.
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1. Tateishi U, Hasegawa T, Onaya H, Satake M, Arai Y, Moriyama N. Myxoinflammatory Fibroblastic Sarcoma: MR Appearance and Pathologic Correlation. AJR Am J Roentgenol. 2005;184(6):1749-53. doi:10.2214/ajr.184.6.01841749 - Pubmed
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2. Narváez J, Martinez S, Dodd L, Brigman B. Acral Myxoinflammatory Fibroblastic Sarcomas: MRI Findings in Four Cases. AJR Am J Roentgenol. 2007;188(5):1302-5. doi:10.2214/AJR.05.0141 - Pubmed
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3. Al-Sakini S. Cytological Features of Myxoinflammatory Fibroblastic Sarcoma. Pathology. 2008;40(5):542-5. doi:10.1080/00313020802197939 - Pubmed
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4. Meis-Kindblom J & Kindblom L. Acral Myxoinflammatory Fibroblastic Sarcoma: A Low-Grade Tumor of the Hands and Feet. Am J Surg Pathol. 1998;22(8):911-24. doi:10.1097/00000478-199808000-00001 - Pubmed
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5. Raghavan V, Satish S, Ravishankar S, Manjunath G. Myxoinflammatory Fibroblastic Sarcoma of the Thigh: A Morphologic Diversity. Avicenna J Med. 2012;2(3):74-6. doi:10.4103/2231-0770.102283 - Pubmed
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5. Jurcić V, Zidar A, Montiel M et al. Myxoinflammatory Fibroblastic Sarcoma: A Tumor Not Restricted to Acral Sites. Ann Diagn Pathol. 2002;6(5):272-80. doi:10.1053/adpa.2002.35738 - Pubmed
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6. Chahdi H, Damiri A, Oukabli M, Albouzidi A, Bouabid S, Lazrek K. Acral Myxoinflammatory Fibroblastic Sarcoma. Orthop Traumatol Surg Res. 2010;96(5):597-9. doi:10.1016/j.otsr.2009.11.018 - Pubmed
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