Neoplasm
Last revised by Daniel J Bell on 19 Jan 2022
Citation, DOI, disclosures and article data
Citation:
Bell D, Rahman F, Neoplasm. Reference article, Radiopaedia.org (Accessed on 16 Apr 2024) https://doi.org/10.53347/rID-90849
Permalink:
rID:
90849
Article created:
30 Jun 2021,
Daniel J Bell ◉
Disclosures:
At the time the article was created Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Last revised:
19 Jan 2022,
Daniel J Bell ◉
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
5 times, by
2 contributors -
see full revision history and disclosures
Systems:
Sections:
Tags:
Synonyms:
- Neoplasia
- Tumour
- Tumor
- Tumors
- Tumours
- Neoplastic disease
- Neoplasms
- Neoplastic diseases
- Benign neoplasm
- Benign neoplasms
Neoplasms, also known as tumors, are pathological masses, caused by cells abnormally proliferating and/or not appropriately dying. Neoplasms may be either benign or malignant. Malignant neoplasms are synonymous with cancers.
Benign neoplasms
- clear origin (unless very large)
- slow growth
- usually well-defined margins
- do not metastasize
- do not invade adjacent organs/tissues
- may transform, i.e. become malignant
- often asymptomatic, increased mortality unlikely
Malignant neoplasms
- origin not always clear
- variable growth, usually faster than benign tumors
- often ill-defined margins
- may metastasize to lymph nodes, distant organs
- may invade adjacent organs/tissues
- often symptomatic and potentially lethal
History and etymology
Neoplasm is derived from two Greek root words, νεος (neos) meaning 'new' and πλασμα (plasma) meaning 'a molded object' 3,4.
References
- 1. Patel A. Benign vs Malignant Tumors. (2020) JAMA oncology. 6 (9): 1488. doi:10.1001/jamaoncol.2020.2592 - Pubmed
- 2. Koten JW, Neijt JP, Zonnenberg BA, Den Otter W. The difference between benign and malignant tumours explained with the 4-mutation paradigm for carcinogenesis. (1993) Anticancer research. 13 (4): 1179-82. Pubmed
- 3. William Alexander Newman Dorland. Dorland's Illustrated Medical Dictionary. (2018) ISBN: 9781416023647
- 4. James Diggle. The Cambridge Greek Lexicon. Volume II. (2021) ISBN: 9781108836982
- 5. C. Simon Herrington. Muir's Textbook of Pathology. (2020) ISBN: 9780367146726
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