Neuhauser sign (distal ileum)

Last revised by Frank Gaillard on 27 Jul 2022

Neuhauser sign refers to a soap bubble appearance seen in the distal ileum in cases of meconium ileus, related to the air mixed with meconium. It may be seen with barium enema if contrast passes beyond the ileocecal valve or with small-bowel follow-through.

Although classically described with meconial ileus, this sign is nonspecific and may be seen in various conditions, including:

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