Neurofibrillary tangles

Last revised by Daniel J Bell on 28 Apr 2020

Neurofibrillary tangles (NFTs) are abnormal cytoplasmic accumulations of tau proteins, found in neuronal and glial cells of the central nervous system. They are responsible for a number of neurodegenerative diseases (collectively known as tauopathies) including 1:

Neurofibrillary tangles are also a prominent feature of Alzheimer disease, which in addition demonstrates extracellular neuritic plaques.

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.