Octreotide scintigraphy
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Octreotide scintigraphy uses 111In-labelled octreotide which is a somatostatin analog; it is also known as an OctreoscanTM, a brand name for 111In-labelled pentetreotide; pentetreotide is a DTPA-conjugated form of octreotide, originally manufactured by Mallinckrodt Nuclear Medicine LLC, which now forms part of Curium). It
It is particularly useful for assessment of neuroendocrine tumours, and the Krenning Score is used to grade these, most commonly for PRRT planning..
Examples include:
- carcinoid tumour
- paraganglioma
- small cell lung cancer
- pituitary adenoma
- neuroblastoma
- medullary thyroid carcinoma
- pancreatic islet cell tumour
Certain non-neuroendocrine tumours can also show uptake in an octreoscan. Examples include:
Also, certain autoimmune or granulomatous diseases may occasionally show octreotide uptake.
-<p><strong>Octreotide</strong><strong> scintigraphy</strong> uses <sup>111</sup>In-labelled octreotide which is a somatostatin analog; it is also known as an Octreoscan<sup>TM</sup>, a brand name for <sup>111</sup>In-labelled pentetreotide; pentetreotide is a DTPA-conjugated form of octreotide, originally manufactured by Mallinckrodt Nuclear Medicine LLC, which now forms part of Curium). It is particularly useful for assessment of <a href="/articles/neuroendocrine-tumours">neuroendocrine tumours</a>.</p><p>Examples include:</p><ul>- +<p><strong>Octreotide</strong><strong> scintigraphy</strong> uses <sup>111</sup>In-labelled octreotide which is a somatostatin analog; it is also known as an Octreoscan<sup>TM</sup>, a brand name for <sup>111</sup>In-labelled pentetreotide; pentetreotide is a DTPA-conjugated form of octreotide, originally manufactured by Mallinckrodt Nuclear Medicine LLC, which now forms part of Curium). </p><p>It is particularly useful for assessment of <a href="/articles/neuroendocrine-tumours">neuroendocrine tumours</a>, and the <a title="Krenning score of neuroendocrine tumour uptake" href="/articles/krenning-score-of-neuroendocrine-tumour-uptake">Krenning Score</a> is used to grade these, most commonly for PRRT planning..</p><p>Examples include:</p><ul>
-<li><a title="Glomus jugulotympanicum paraganglioma" href="/articles/glomus-jugulotympanicum-paraganglioma">glomus jugulotympanicum</a></li>- +<li><a href="/articles/glomus-jugulotympanicum-paraganglioma">glomus jugulotympanicum</a></li>
-<li><a href="/articles/small-cell-lung-cancer-2">small cell lung cancer</a></li>- +<li><a href="/articles/small-cell-lung-cancer-4">small cell lung cancer</a></li>
-<a title="Merkel cell carcinoma" href="/articles/merkel-cell-carcinoma">Merkel cell carcinoma</a> <sup>3</sup>- +<a href="/articles/merkel-cell-carcinoma">Merkel cell carcinoma</a> <sup>3</sup>
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